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    Research and Clinical
    Nicole Ladesich, MHSA

    Research Site Director/Clinical Research Coordinator

    10995 Quivira Road

    Overland Park, KS 66210

    Nicole has over 14 years of experience in clinical trial research management and operations. Areas of expertise include Phase I-IV industry sponsored and investigator initiated clinical trials (medical device and drug development), regulatory affairs, and monitoring for both academic institutions, clinical research and site management organizations. Nicole’s background includes working as a Clinical Research Coordinator, Clinical Trial Monitor, Regulatory Site Start-Up Specialist and as a Project Manager. Therapeutic areas of experience include pain and joint management, cardiovascular, CNS-psychiatric, endocrinology, infectious disease, pulmonary, rheumatology, urology and woman’s health. She has facilitated and supported submissions of internal and extramural National Institutes of Health (NIH) infrastructure grants for academic research. In 2008, Nicole received her Masters Degree in Hospital Administration from the University of Kansas Medical Center, School of Medicine. During her graduate studies, she received the Peter T. Bohan Medical School Scholarship for academic excellence. She holds a Bachelors degree in Communication Studies. Nicole has managed both domestic and global clinical trials. She is responsible for maintenance of all regulatory documents, IRB submissions, patient enrollment and recruitment, and conduct of study procedures in accordance with study protocols and database management. Nicole is a member of the local Kansas City chapter of the Association of Clinical Research Professionals (ACRP) and is currently working toward receiving her CCRP certification. Her passion is to uphold the mission of managing clinical research activities for Kansas Pain Management (d/b/a Neuroscience Research Center, LLC), part of which is to exceed expectations to increase the quality of life for a patient’s well-being.

    Current Studies and Clinical Trials

    Chronic Abdominal Pain :

    Chronic Abdominal Pain: We are currently enrolling the patients who suffer from chronic Abdominal pain who have failed treatment with multiple medications. We are the part of multicenter clinical trial to see if these patients could benefit from high frequency spinal cord stimulation device. For details of this device please visit Nevro.com

    Neuropathic pain after Knee replacement surgery and Chronic groin pain after inguinal hernia surgery :

    Subset of patients who have persistent pain after surgery might benefit from High Frequency Spinal cord Stimulation device. For details of this device visit Nevro.com. Kansas pain Management is the part of multicenter clinical trial. Encouraged by the results, the study has been presented at prestigious national and international conferences.

    Spinal Stenosis Study :

    Kansas Pain Management is accepting new participants for the Registry. If you are 55 or older and think you may have spinal stenosis – but are not yet ready for major spine surgery – this study may be right for you. The study is for the Vertiflex device a minimally-invasive alternative to traditional spine surgery that does not require general anesthesia and allows most patents to return home the same day. For details visit Vertiflexspine.com

    Sacroiliatis :

    Patient who have history of Chronic Low Back and Buttock Pain with diagnosis of Sacroiliatis may benefit from Endoscopic Sacroiliac Joint Radiofrequency Ablation. Kansas Pain Management is a part of multicenter clinical trial. For details of device visit Joimax.com

    Past Studies and Clinical Trials

    Lumbar Radiculopathy and Failed Back Surgery Syndrome :

    Patients who have persistent back and leg pain after back surgery might benefit from Spinal Cord Stimulator device. Kansas Pain Management was a part of multicenter study. We have successfully completed enrollment for the study in 2017. For details of the device visit Bostonscientific.com
    Current Studies
    Current Trials

    If you are interested in learning more please call 913-825-2314 or 913-825-2315.

    Osteoarthritis of the Knee

    We are currently enrolling patients diagnosed with osteoarthritis of the knee with pain that has been present for at least 6 months. Patients must also have a history indicating insufficient pain relief from conservative treatments (medications, physical therapy, intra-articular treatment with corticosteroids) and have not had significant trauma or surgery to the knee in the past year. We are part of a multicenter clinical trial to see if these patients could benefit from an intra-articular injection into the knee.

    Lumbar and Lumbosacral Radiculopathy

    We are currently enrolling patients with a primary diagnosis of unilateral lumbar and/or lumbosacral radiculopathy. Patients must have had no significant improvement following a minimum of 8 weeks of mechanical intervention (physical therapy, chiropractic treatment, etc.) or over-the-counter analgesics (topical patches/creams/gels, NSAIDS). Additionally, patients cannot have a history of lumbar surgery and/or intradiscal interventions. Also, cannot have received an ESI, nerve block, or other similar procedure in the lumbosacral area performed in the past 8 weeks. We are part of a multicenter clinical trial to see if these patients could benefit from an injection in lumbar and lumbosacral epidural space.

    Moderate Degenerative Lumbar Stenosis

    We are currently enrolling patients 45 years or older who suffer from pain, numbness, and/or cramping in their legs. Patients must have persistent leg/ buttock/ groin pain, with or without back pain that is consistently relieved by flexion activities (such as sitting or bending over a shopping cart). We are part of a multicenter clinical trial to see if these patients could benefit from an implanted device into the lower back.

    Diabetic Peripheral Neuropathy of the Feet

    We are currently enrolling patients with diabetic peripheral neuropathy of the feet. This study aims to assess the long-term effectiveness of high dose capsaicin patches for the treatment of pain associated with diabetic peripheral neuropathy.

    Post-Surgical Neuropathic Pain

    Kansas Pain Management is accepting patients with moderate to severe post-surgical pain with a duration of at least 6 months. We are part of a multicenter clinical trial to see if these patients could benefit from a patch application on the painful skin area.

    Neck Pain and Headache

    We are currently enrolling patients with at least a 6-month history of axial neck pain and symptoms consistent with cervicogenic headache who have not had relief from conservative treatments (medications, physical therapy, chiropractic care, etc.). We are assessing if these patients receive pain relief from Radiofrequency Ablation. 

    Chronic Low Back Pain and/or Leg Pain

    We are currently enrolling patients that have been diagnosed with chronic, intractable pain of the back with or without leg pain. This study aims to assess the pulse dose settings of patients with a spinal cord stimulator.

    If you are interested in learning more please call 913-825-2314 or 913-825-2315.